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Exploring CBD As A Treatment For Alzheimer’s Disease

Exploring CBD As A Treatment For Alzheimer's Disease
Written by PsychePen

How could CBD’s anti-inflammatory properties contribute to new treatments for Alzheimer’s disease?

Summary: A new study suggests that CBD (cannabidiol) may offer significant benefits in preventing and alleviating Alzheimer’s disease. Researchers from China Pharmaceutical University have found that CBD enhances cognitive function and offers protection against the protein A?1–42, a biomarker associated with Alzheimer’s onset. The study, titled “Assessing Cannabidiol as a Therapeutic Agent for Preventing and Alleviating Alzheimer’s Disease Neurodegeneration,” was published in the journal Cells.

New Research Highlights CBD as a key element in Alzheimer’s Prevention and Treatment

Cannabidiol, widely known for its array of potential benefits, including pain relief and anti-seizure properties, is now being explored for its effectiveness against Alzheimer’s disease. The study conducted by researchers at China Pharmaceutical University delves into the neuroprotective and anti-inflammatory mechanisms of CBD. With the number of people over 65 with Alzheimer’s projected to reach 12.7 million by 2050, the urgency to find effective treatments is paramount.

Alzheimer’s, a progressive disease characterized by brain changes leading to memory loss and other mental impairments, has no known cure. However, CBD’s anti-inflammatory properties have shown promise in experimental models. The researchers used mice to model Alzheimer’s disease using A?1–42 and conducted RNA-seq analysis to understand CBD’s actions.

The study revealed that CBD did not cause significant damage or cell death. Instead, it appeared to counteract cognitive and memory impairments induced by A?1–42. In the Morris water maze test, used to assess cognitive functions and memory in rodents, mice treated with CBD showed improved performance, indicating better cognitive function and spatial memory.

The findings suggest CBD’s efficacy in moderating microglial and astrocytic activation, offering anti-inflammatory benefits that protect synaptic function and alleviate cognitive deficits associated with Alzheimer’s. The study provides insights into CBD’s role in modulating critical genes within the inflammatory reaction, highlighting its robust anti-inflammatory potential.

Researchers estimate the equivalent human dose from the study to be about 115 mg of CBD, suggesting its viability as an oral supplement. However, CBD’s role in combating Alzheimer’s is still absent from contemporary guidelines. The study concludes by emphasizing CBD’s potential in either preventing or mitigating the effects of Alzheimer’s, suggesting future formulations of CBD supplements could include indications for Alzheimer’s prevention and alleviation.

Source: Culture Magazine, The study

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AI Disclaimer: This news update was created using a AI tools. PsychePen is an AI author who is constantly improving. We appreciate your kindness and understanding as PsychePen continues to learn and develop. Please note that the provided information is derived from various sources and should not be considered as legal, financial, or medical advice.

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About the author


PsychePen is Cannadelics' main news editor. As a self-taught wellness expert with a unique perspective on drugs, cannabis, and psychedelics, PsychePen is known for his unique style: short and informative articles, easy-to-read and to-the-point. PsychePen is also one of our most successful AI authors. so its keep on improving.