Many cannabis users will tell you, that once in a while, a vital “T-Break” (THC) is needed to recharge after tolerance is built up. But does the same principle also apply to CBD?

Is there such a thing as CBD tolerance? First thing’s first: THC is the psychoactive compound in cannabis that makes you high and then sleepy, and is favoured by recreational users for its effects. CBD on the other hand, and here we mean CBD products such as CBD oils, topicals and drops, is being used increasingly, as nothing more than a health aid, by thousands of people across the globe.

CBD oils or drops offer no heady effects whatsoever, but do help people with stress, anxiety, depression, as well as sleep disorders and a whole host of other medical issues and conditions. While research on CBD tolerance is thin to say the least, it is out there, and we dug nice and deep to find it…

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With THC, before long, the THC receptors in the human brain and body begin to become essentially saturated, and the effects of the cannabis tends to become muted and less potent than at first. Some THC enthusiasts will simply switch to a new strain at this point, while others will opt for a a week’s break in order to let the receptors recover. The same is not true of CBD.

In one study, mice were split into two groups; they were given THC and CBD immediately before and three hours after cerebral ischemia. That group were given the CBD only once, while the second group received it for 14 days continuously. The study concluded that the mice who received the CBD consecutively did NOT develop a tolerance to the substance, although they did where THC was concerned.

Another study, entitled, “Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent,” showed that CBD tolerance doesn’t develop due mechanisms inside the body which regulate tolerance. The study may not be conclusive proof, however it does go some way to prove that CBD does not affect tolerance in the same way as THC or many conventional drugs on the market.

Always ensure you use only the highest quality CBD products available, preferably ones which have lab test results confirming their authenticity.

We has asked Dr. Leah Zachar, our medical adviser, to confirm that using CBD does not lead to tolerance issues, this is her answer:

“When it comes to delivery systems, CBD does not produce tolerance whether it is vaped, used sublingually as an oil, applied to the skin as a balm, or taken orally as an edible or softgel.” (Dr. Leah Zachar)