We have reached a turning point in the cannabis industry, where, as consumers, we now have more choices than we know what to do with. When I was younger, shopping for weed consisted of calling one of the 3 or 4 dealers in my area and picking up whatever flower strain was available from whoever had the best product or lowest price, or a combination of the two. Now, whether you live in a legal state or not, you have options – from classic flowers, to vape products, edibles, topicals, and so much more.
Obviously, legal markets are rife with product variety, but even in prohibition states you can check out smoke shops, gas stations, or online retailers and find a myriad of alternative cannabinoids; some intoxicating and some not; some safe and some sketchy. The more popular products are often those containing blends of three or more different cannabinoid and terpene compounds.
According to recent surveys, nearly half of all cannabis consumers prefer to use products that contain more than one cannabinoid, among the most popular being 1:1 blends. Knowing what we know about the entourage effect and how different plant compounds work together synergistically to provide the highest level of benefits, it’s no surprise that people are excited to try new mixes. But how exactly do these blends work? What are the best combinations? And what different effects can you expect to experience?
Cannabis science has come a really long way since the initial discovery of individual cannabinoids back in the 1940s. To this day we continue to uncover new and exciting things about this incredible plant. Remember to subscribe to The Cannadelics Weekly Newsletter all the latest news and industry stories, as well as exclusive deals on flowers, vapes, edibles, and other products. Also save big on Delta 8, Delta 9 THC, Delta-10 THC, THCO, THCV, THCP & HHC products by checking out our “Best-of” lists!
Alright, so maybe you weren’t expecting math terms in your weed article, but in this case, at least it’s a simple concept. A ratio is a measurement of comparison, and is written with one side against the other. In terms of cannabis products, it generally denotes the amount of THC vs CBD in milligrams, though it can account for any comparison between any compounds. THC and CBD are the two main cannabinoids of the cannabis plant, but some formulations will contain high enough levels of CBN or CBC, for example, that they are included in the ratio.
A 1:2 ratio means that for every one milligram on the first side, there are two on the other. So a product with a THC/CBD ratio of 1:2 could have 6mg of THC to 12mg of CBD or 8mg of THC to 16mg of CBD. A ratio always has the compounds it refers to listed, and goes according to order. If its THC/CBD, then the first number in the ratio is for THC, and the second is for CBD. If the letters are switched, then the accompanying numbers switch sides as well.
Let’s say you have a ratio of THC/CBD 10:2 Then a product with such a formulation could have 20mg of THC to 8mg of CBD. Or maybe you have a product with a 5:1:1 ratio, and that could be 25mg of THC with 5mg of CBD and 5mg of CBN. The 1:1 ratio refers to products that have equal amounts of two different cannabinoids. Typically this refers to Delta 9 THC and CBD, but can be other compounds as well. Another popular blend, especially for sleep and relaxation, is Delta 8 THC and CBN. The amount is whatever a producer decides on, but it only counts as a 1:1 ratio if it’s the same on both sides, for example 15mg of THC paired with 15mg of CBD.
Sometimes the amounts are just slightly off, giving one a tiny edge over the other, but still close to this general ratio. Think of a product that contains 20mg of THC and 19mg of CBD. It’s not exactly the same, but rather than looking at it as a ratio of 20:19, we can also consider this a 1:1.
The Entourage Effect
First noted in 1998 by Professors Raphael Mechoulam and Shimon Ben-Shabat, the entourage effect is a mechanism by which plant compounds work together, often resulting in more noticeable effects compared to when they are isolated and used individually. With cannabis, the entourage effect refers to the way different cannabinoids, terpenes, and flavonoids offer the best health benefits and psychoactive effects when combined, and only when consuming the entire plant in its natural state.
This has been attributed to the way the combination of compounds increases the activity of CB receptors one and two. Because these receptors are found throughout the entire body, the human endocannabinoid system plays a critical role in modulating many different physiological functions such as immune response, sleep/wake cycles, appetite, communication between cells, mental health, and more.
In 2001, two highly notable researchers Ethan Russo (MD, is a board-certified neurologist, psychopharmacology researcher, and author) and John McPartland (DO, MS, University of Vermont, Department of Family Medicine), published a paper titled “Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts.” This research paper revisits the claims of Mechoulam and Ben-Shabat regarding how cannabinoids act with other cannabinoids, as well as their interactions with secondary compounds such as terpenes and flavonoids.
Their research found supporting evidence that “extracts rich in both cannabinoids and terpenes increased pharmacological activities that strengthened and broadened clinical applications and improved the therapeutic index.” Simply put, the effects all-around are better when these compounds are allowed to do what they do naturally and work together.
A Few 1:1 and Blended Products For You to Try
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Delicious 1:1 THC:CBD peach ring gummies with a total of 30mg of cannabinoids each. Made with full spectrum extract, you can save big if you bundle up. Only $1.49 per ring when you buy the 20 pack!
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These 1:1 THC:CBD chocolate chip cookies contain 40 mg of both Delta 9 THC and CBD, making for a very relaxing buzz. Each cookie comes with 2 servings, but 1/4 is enough for most people.
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This tincture contains 1000mg of Delta 8 THC and 1000mg of CBD for a total of 2000mg of cannabinoids (also all natural and vegan). This is potent but mellow (because of the equal ratios), so it’s great for many different types of consumers. Tinctures are discreet, and one of the healthiest ways to consume cannabinoids. Get each bottle for only $22.49 using our coupon code!
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